1027591-10-1

Basic information

• Product Name: 3-chloro-10H-indolo[3,2-b]quinoline-11-carboxylic acid
• Synonyms: 3-chloro-10H-indolo[3,2-b]quinoline-11-carboxylic acid
• CAS NO: 1027591-10-1
• Molecular Weight: 296.713
• Mol File: 1027591-10-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-chloro-10H-indolo[3,2-b]quinoline-11-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3-chloro-10H-indolo[3,2-b]quinoline-11-carboxylic acid(1027591-10-1)
• EPA Substance Registry System: 3-chloro-10H-indolo[3,2-b]quinoline-11-carboxylic acid(1027591-10-1)

Safety Data

• Hazardous Substances Data: 1027591-10-1(Hazardous Substances Data)

Upstream product

• 6341-92-0 6-chloroisatin 
• 608-08-2 3-indoxyl acetate 
• 16800-67-2 N,O-diacetylindoxyl 

Relevant articles and documents

Identification of 3-phenylaminoquinolinium and 3-phenylaminopyridinium salts as new agents against opportunistic fungal pathogens

Previous studies on the indoloquinoline alkaloid, cryptolepine (2), revealed that it has antii-nfective properties among other activities. Using Structure-activity relationship (SAR) techniques, several ring-opened analogs of cryptolepine (3-phenylaminopyridinium and 3-phenylaminoquinolinium derivatives) were designed to improve the potency and lower the cytotoxicity shown by several of the precursor agents. Results indicate that these ring-opened analogs constitute new anti-infective agents with over a 100-fold potency and several fold lower cytotoxicity than cryptolepine from which they are derived.