1027642-32-5Relevant academic research and scientific papers
Preparation of potassium alkoxymethyltrifluoroborates and their cross-coupling with aryl chlorides
Molander, Gary A.,Canturk, Belgin
supporting information; experimental part, p. 2135 - 2138 (2009/05/26)
(Chemical Equation Presented) A wide variety of alkoxymethyltrifluoroborate substrates were prepared via SN2 displacement of potassium bromomethyltrifluoroborate with various alkoxides in excellent yields. These alkoxymethyltrifluoroborates were effectively cross-coupled with several aryl chlorides. This method provides a unique dissonant disconnect that allows greater flexibility in the design of new and improved synthetic pathways.
