1027754-42-2Relevant academic research and scientific papers
Synthesis of Imidazolinium Salts by Pd/C-Catalyzed Dehydrogenation of Imidazolidines
Ando, Shin,Ishizuka, Tadao,Xiao, Bowen
supporting information, p. 4551 - 4554 (2021/08/30)
A method for the synthesis of imidazolinium salts through a catalytic dehydrogenation was developed using Pd/C as a catalyst with ammonium salt as an additive. Optimization of the reaction conditions revealed the existence of a proton source that was necessary to accomplish the reaction. Under the optimal conditions, oxidation-sensitive components, such as an allyl, a furan, and a thiophene can be introduced into the corresponding imidazolinium salts. In addition to the varied N-substituents, the presented method can be used to synthesize a series of 2-substituted imidazolinium salts.
New pinene-derived pyridines as bidentate chiral ligands
Malkov, Andrei V.,Stewart-Liddon, Angus J.P.,Teply, Filip,Kobr, Luká?,Muir, Kenneth W.,Haigh, David,Ko?ovsky, Pavel
, p. 4011 - 4025 (2008/09/20)
A synthesis of new bidentate pyridines 8a-d, 9, and 10 has been developed, starting from triflate 14, readily available from β-pinene 11. A copper complex of the pyridine-oxazoline ligands 8a has been found to catalyze asymmetric allylic oxidation of cyclic olefins 36a-c with good conversion rates and acceptable enantioselectivity (≤67% ee). The imidazolium salt 10 has been identified as a precursor of the corresponding N,N′-unsymmetrical N-heterocyclic carbene ligand, whose complex with palladium catalyzed the intramolecular amide enolate α-arylation leading to oxindole 45 in excellent yield but with low enantioselectivity.
