1027770-98-4Relevant academic research and scientific papers
Synthesis of complex allylic esters via C-H oxidation vs C-C Bond formation
Vermeulen, Nicolaas A.,Delcamp, Jared H.,White, M. Christina
supporting information; experimental part, p. 11323 - 11328 (2010/10/04)
A highly general, predictably selective C-H oxidation method for the direct, catalytic synthesis of complex allylic esters is introduced. This Pd(II)/sulfoxide-catalyzed method allows a wide range of complex aryl and alkyl carboxylic acids to couple directly with terminal olefins to furnish (E)-allylic esters in synthetically useful yields and selectivities (16 examples, E/Z ≤ 10:1) and without the use of stoichiometric coupling reagents or unstable intermediates. Strategic advantages of constructing allylic esters via C-H oxidation vs C-C bond-forming methods are evaluated and discussed in four case studies.
A facile microwave assisted synthesis and antimicrobial activities of naturally occurring (E)-cinnamyl (E)-cinnamates and (E)-aryl cinnamates
Mahajan, Rajesh P,Patil, Ulhas K,Patil, Shamkant L
, p. 1459 - 1465 (2008/09/18)
Benzaldehydes 1a-e on reaction with phosphorane 3 and aldehydes 2a-e with phosphorane 4 under microwave irradiation provide the (E)-cinnamyl (E)-cinnamates 5a-e and (E)-aryl cinnamates 6a-e respectively in high yield. Cinnamates 5a-e and 6a-e exhibit antibacterial and antifungal activity.
