102779-37-3

Upstream product

• 859-07-4 cephaloram 
• 103-80-0 phenylacetyl chloride 
• 957-68-6 7-Aminocephalosporanic acid 

Downstream Products

• 362673-24-3 (7R,7aR)-4-(tert-butoxycarbonyl)-1,6-dioxo-7-[(2-phenylacetyl)amino]-1,6,7,7a-tetrahydro-2H-1λ⁴-azeto[2,1-b][1,3]thiazine-3-carboxylic acid 
• 142967-22-4 tert-butyl (7R,7aR)-3-(hydroxymethyl)-1,6-dioxo-7-[(2-phenylacetyl)amino]-1,6,7,7a-tetrahydro-2H-1λ⁴-azeto[2,1-b][1,3]thiazine-4-carboxylate 
• 362673-21-0 tert-butyl (7R,7aR)-3-formyl-1,6-dioxo-7-[(2-phenylacetyl)amino]-1,6,7,7a-tetrahydro-2H-1λ⁴-azeto[2,1-b][1,3]thiazine-4-carboxylate 
• 74639-35-3 (5S,6R,7R)-3-Hydroxymethyl-5,8-dioxo-7-phenylacetylamino-5λ⁴-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid 

Relevant academic research and scientific papers

A new convenient synthesis of 3-carboxycephems starting from 7-aminocephalosporanic acid (7-ACA)

New convenient syntheses of 3-carboxycephems starting from 7-ACA are reported. All three possible cephem derivatives with respect to the position of the double bond in the six-membered ring and oxidation state of the sulfur atom have been synthesized in high overall yield.