102779-39-5

Basic information

• Product Name: C₁₀₂H₁₈₅Cl₂O₁₈PSi₂
• CAS NO: 102779-39-5
• Molecular Weight: 1857.63
• Mol File: 102779-39-5.mol

Chemical Properties

• CAS DataBase Reference: C₁₀₂H₁₈₅Cl₂O₁₈PSi₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₀₂H₁₈₅Cl₂O₁₈PSi₂(102779-39-5)
• EPA Substance Registry System: C₁₀₂H₁₈₅Cl₂O₁₈PSi₂(102779-39-5)

Safety Data

• Hazardous Substances Data: 102779-39-5(Hazardous Substances Data)

Upstream product

• 102728-42-7 3-O-<3,4-O-(tetraisopropyldisiloxane-1,3-diyl)-β-D-glucopyranosyl>-1,2-di-O-oleoyl-sn-glycerol 
• 102728-44-9 1,2-di-O-stearoyl-sn-glycero-3-phospho-(2,4-dichlorophenol) 

Relevant articles and documents

SYNTHESIS OF PHOSPHATIDYL-β-GLUCOSYL GLYCEROL CONTAINING A DIOLEOLYL DIGLYCERIDE MOIETY. APPLICATION OF THE TETRAISOPROPYLDISILOXANE-1,3-DIYL (TIPS) PROTECTING GROUP IN SUGAR CHEMISTRY. PART IV

The preparation of phosphatidyl-β-glucosyl diglyceride 12c is described.The synthesis of glycophospholipid 12c was accomplished by using: (a) the levulinoyl group for the temporary protection of the glucose hydroxyl functions of 6b, which could then be converted into the dioleoyl substituted derivative 7c; (b) the tetraisopropyldisiloxane-1,3-diyl (TIPS) group to protect the 3'- and 4'-hydroxyl groups of 7c, in a two step procedure, to afford compound 8; (c) a 2,4-dichlorophenyl protected phosphatidic acid derivative 11.Compound 11 could be selectively coupled to the primary hydroxyl function of 8 to afford the fully protected glycophospholipid 12a.Finally, removal of the 2,4-dichlorophenyl and TIPS protecting groups from 12a was performed with syn-4-nitrobenzaldoximate and fluoride ions, respectively, to afford glycophospholipid 12c.