10279-85-3

Upstream product

• 33531-75-8 3a-benzo[1,3]dioxol-5-yl-1-benzyl-(3ar,7ac)-octahydro-indol-6t-ol 
• 32209-88-4 3a-benzo[1,3]dioxol-5-yl-1-benzyl-(3ar,7ac)-octahydro-indol-6-one 
• 114047-11-9 Acetic acid (3aS,6S,7aS)-3a-benzo[1,3]dioxol-5-yl-1-benzyl-octahydro-indol-6-yl ester 
• 50-00-0 formaldehyd 
• 114047-13-1 (3aS*,6S*,7aS*)-6-acetoxy-3a,4,5,6,7,7a-hexahydro-3a-(3',4'-methylenedioxyphenyl)indoline 
• 32209-89-5 cis-6-hydroxy-3a-(3,4-methylenedioxyphenyl)-2,3,3a,4,5,6,7,7a-octahydro-1H-indole 
• 33531-75-8 3a-benzo[1,3]dioxol-5-yl-1-benzyl-(3ar,7ac)-octahydro-indol-6c-ol 
• 114047-11-9 Acetic acid (3aS,6R,7aS)-3a-benzo[1,3]dioxol-5-yl-1-benzyl-octahydro-indol-6-yl ester 
• 114047-13-1 (3aS*,6R*,7aS*)-6-acetoxy-3a,4,5,6,7,7a-hexahydro-3a-(3',4'-methylenedioxyphenyl)indoline 
• 33531-78-1 (3aR^*,6R^*,7aS^*)-3a-(1,3-benzodioxol-5-yl)octahydroindole-6-ol 
• 4439-02-5 3,4-methylenedioxyphenylacetonitrile 
• 148614-09-9 (Z)-2-(3,4-methylenedioxyphenyl)-6-trimethylsilyl-5-hexenenitrile 
• 148614-10-2 (Z)-2-(chloroethyl)-2-(3,4-methylenedioxyphenyl)-6-trimethylsilyl-5-hexenenitrile 
• 96400-90-7 4-Benzo[1,3]dioxol-5-yl-4-((Z)-4-trimethylsilanyl-but-3-enyl)-3,4-dihydro-2H-pyrrole 

Relevant academic research and scientific papers

THE IMPORTANCE OF VINYLSILANE STEREOCHEMISTRY AND ?-? STABILIZATION IN IMINIUM ION-VINYLSILANE CYCLIZATIONS. A SHORT TOTAL SYNTHESIS OF THE AMARYLLIDACEAE ALKALOID (+/-)-EPIELWESINE.

cis-3a-Aryl-2,3,3a,4,5,7a-hexahydro-1H-indoles 5 and 10 are formed in excellent yield from acid promoted cyclization of (Z)-vinylsilane imines 3 and 9.The failure of the corresponding (E)-vinylsilane isomer 4 to cyclize under similar condition demonstrate

TOTAL SYNTHESIS OF THE AMARYLLIDACEAE ALKALOID (+/-)-EPIELWESINE. THE IMPORTANCE OF VINYLSILANE STEREOCHEMISTRY IN IMINIUM ION-VINYLSILANE CYCLIZATIONS

(+/-)-Epielwesine (9) was prepared in an efficient and completely stereocontrolled fashion in six steps and 28percent overall yield from commercially available 3,4-methylenedioxyphenylacetonitrile (15a).The key step is acid promoted cyclization of the (Z)

Synthesis of Sceletium and Amaryllidaceae Alkaloids, (+/-)-Mesembrine and (+/-)-Dihydromaritidine, (+/-)-Epidihydromaritidine, (+/-)-Elwesine, and (+/-)-Epielwesine

The alkylation of 2-arylcyclohexanones (12b and 6) with alkyl halides or acrylonitrile and 50percent aq. sodium hydroxide in the presence of a phase-transfer catalyst (18-crown-6) was found to give readily 2-alkyl-2-arylcyclohexanones (14 and 16) in fair