1027953-74-7

Upstream product

• 58871-09-3 6-O-tert-butyldimethylsilyl-D-glucal 
• 13265-84-4 D-glucal 
• 1053244-28-2 2-(tert-butyl-dimethyl-silanyloxymethyl)-4-triisopropylsilanyloxy-3,4-dihydro-2H-pyran 
• 1053650-78-4 Trifluoro-methanesulfonic acid (2S,4S)-6-methoxy-4-triisopropylsilanyloxy-tetrahydro-pyran-2-ylmethyl ester 
• 1026169-62-9 Acetic acid 2-formyl-3-((2R,4S)-6-methoxy-4-triisopropylsilanyloxy-tetrahydro-pyran-2-ylmethyl)-phenyl ester 

Relevant academic research and scientific papers

Carbohydrate-based routes to salicylate natural products: Formal total synthesis of (+)-apicularen A from D-glucal

A synthesis of apicularen analogue (-)-4 in 18 steps from D-glucal is reported. As (+)-4 has been converted into apicularen A in 8 steps, this constitutes a formal total synthesis of this potent naturally occurring anti-cancer agent.