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1027964-02-8

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1027964-02-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1027964-02-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,7,9,6 and 4 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1027964-02:
(9*1)+(8*0)+(7*2)+(6*7)+(5*9)+(4*6)+(3*4)+(2*0)+(1*2)=148
148 % 10 = 8
So 1027964-02-8 is a valid CAS Registry Number.

1027964-02-8Upstream product

1027964-02-8Relevant articles and documents

Selective Inhibitors of Monoamine Oxidase. 2. Arylamide SAR

Harfenist, Morton,Joyner, Charles T.,Mize, Patrick D.,White, Helen L.

, p. 2085 - 2089 (1994)

Monoamine oxidase (MAO) exists in two forms distinguishable by substrate specificity.Inhibition of MAO A is believed to be responsible for the antidepressant activity of MAO inhibitors.A group of N-arylacetamides are highly specific inhibitors of MAO A, some with IC50 values in the 10-100 nM range.The requirements for high activity and specificity include a nearly linear tricyclic aromatic portion but a larger and a smaller central ring component.The amide group, which is best acetamido, is optimally placed para to the smaller central group.The size and shape of the aromatic moiety appear to be the major influence on activity and specificity for MAO A.

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