1027985-84-7Relevant academic research and scientific papers
5-Lipoxygenase inhibitors: Synthesis and structure-activity relationships of a series of 1-aryl-2H,4H-tetrahydro-1,2,4-triazin-3-ones
Bhatia, Pramila A.,Brooks, Clint D. W.,Basha, Anwer,Ratajczyk, James D.,Gunn, Bruce P.,Bouska, Jennifer B.,Lanni, Carmine,Young, Patrick R.,Bell, Randy L.,Carter, George W.
, p. 3938 - 3950 (2007/10/03)
Synthetic routes were developed to access a variety of novel 1-aryl- 2H,4H-tetrahydro-1,2,4-triazin-3-one analogs which were evaluated as 5- lipoxygenase (5-LO) inhibitors. The parent structure, 1-phenylperhydro- 1,2,4-triazin-3-one (4), was found to be a
