1028108-04-4Relevant articles and documents
1,4,5,6,7,8-Hexahydroquinolines and 5,6,7,8-tetrahydronaphthalenes: A new class of antitumor agents targeting the colchicine binding site of tubulin
El-Emam, Ali A.,El-Gohary, Nadia S.,Shaheen, Mennatallah A.
, (2020)
New series of 2-amino-1,4,5,6,7,8-hexahydroquinoline-3-carbonitriles 3a,b and 2-amino-5,6,7,8-tetrahydronaphthalene-1,3-dicarbonitriles 4a-h were synthesized and evaluated for their antitumor activity. In vitro antitumor screening of the new members again
Efficient NaOH-catalyzed reaction of aromatic aldehyde, cyclic ketones, and malononitrile under solvent-free conditions using a grinding method
Rong, Liangce,Han, Hongxia,Jiang, Hong,Tu, Shujiang
, p. 3530 - 3542 (2008/12/23)
An efficient and facile synthesis of 2,6-dicyanoanilines via a one-pot reaction of aromatic aldehydes, malononitrile, and cyclic ketones in the presence of NaOH under solvent-free conditions using a grinding method has been developed. Compared with the classical reaction conditions, the new synthetic method has the advantages of excellent yields, shorter reaction times, and mild reaction conditions. Copyright Taylor & Francis Group, LLC.