1028281-09-5

Basic information

• Product Name: BOC-D-THREO-3-(4-CYANOPHENYL)SERINE
• Synonyms: BOC-D-THREO-3-(4-CYANOPHENYL)SERINE;ANKVSTYQCCCVHX-NWDGAFQWSA-N
• CAS NO: 1028281-09-5
• Molecular Formula: C₁₅H₁₈N₂O₅
• Molecular Weight: 306.31
• Mol File: 1028281-09-5.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 541.1±50.0 °C(Predicted)
• Appearance: /
• Density: 1.30±0.1 g/cm3(Predicted)
• PKA: 3.33±0.10(Predicted)
• CAS DataBase Reference: BOC-D-THREO-3-(4-CYANOPHENYL)SERINE(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-D-THREO-3-(4-CYANOPHENYL)SERINE(1028281-09-5)
• EPA Substance Registry System: BOC-D-THREO-3-(4-CYANOPHENYL)SERINE(1028281-09-5)

Safety Data

• Hazardous Substances Data: 1028281-09-5(Hazardous Substances Data)

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 

Relevant articles and documents

A CD exciton chirality method for determination of the absolute configuration of threo-β-aryl-β-hydroxy-α-amino acid derivatives

The absolute configuration of threo-β-aryl-β-hydroxy-α-amino acids was studied by CD exciton chirality method using 7-diethylaminocoumarin-3-carboxylate as a red-shifted chromophore. Bischromophoric derivatives for a series of threo-β-aryl-β-hydroxy-α-amino acids (3a-h) were prepared and their CD spectra measured in CH2Cl2. By combining the data of CD and NMR coupling constants, we are able to correlate their preferred conformer (B) and the positive CD to the corresponding (2S,3R)-absolute configuration. These results are consistent with those obtained from serine and threonine derivatives, which represent the simplest form of β-hydroxy-α-amino acids. This CD method could thus become a general method for determining the absolute configuration of threo-β-aryl-β-hydroxy-α-amino acids.