1028282-95-2Relevant academic research and scientific papers
Design, synthesis, and evaluation of nonpeptidic inhibitors of human rhinovirus 3C protease
Webber, Stephen E.,Tikhe, Jayashree,Worland, Stephen T.,Fuhrman, Shella A.,Hendrickson, Thomas F.,Matthews, David A.,Love, Robert A.,Patick, Amy K.,Meador, James W.,Ferre, Rose Ann,Brown, Edward L.,Delisle, Dorothy M.,Ford, Clifford E.,Binford, Susan L.
, p. 5072 - 5082 (2007/10/03)
The design, synthesis, and biological evaluation of reversible, nonpeptidic inhibitors of human rhinovirus (HRV) 3C protease (3CP) are reported. A novel series of 2,3-dioxindoles (isatins) were designed that utilized a combination of protein structure-bas
