1028295-53-5Relevant academic research and scientific papers
Non-peptide glycoprotein IIb/IIIa antagonists. 11. Design and in vivo evaluation of 3,4-dihydro-1(1H)-isoquinolinone-based antagonists and ethyl ester prodrugs
Hutchinson, John H.,Cook, Jacquelynn J.,Brashear, Karen M.,Breslin, Michael J.,Glass, Joan D.,Gould, Robert J.,Halczenko, Wasyl,Holahan, Marie A.,Lynch, Robert J.,Sitko, Gary R.,Stranieri, Maria T.,Hartman, George D.
, p. 4583 - 4591 (2007/10/03)
The structure-activity relationship of a series of orally active glycoprotein IIb/IIIa antagonists containing a nitrogen heterocycle grafted onto a 3,4-dihydro-1(1H)-isoquinolinone core is described. These compounds are structurally novel analogs of the p
