102830-75-1

Basic information

• Product Name: 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE
• Synonyms: 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE;2-Methoxy-3-Bromo-5-Chloropyridine;Pyridine,3-bromo-5-chloro-2-methoxy-
• CAS NO: 102830-75-1
• Molecular Formula: C₆H₅BrClNO
• Molecular Weight: 222.47
• Product Categories: Pyridine;Boronic Acid;Pyridine Series;Indoles ,Indazoles
• Mol File: 102830-75-1.mol
• Article Data: 6

Chemical Properties

• Melting Point: 49.0 to 53.0 °C
• Boiling Point: 215.803 °C at 760 mmHg
• Flash Point: 84.315 °C
• Appearance: /
• Density: 1.65 g/cm³
• Vapor Pressure: 0.212mmHg at 25°C
• Refractive Index: 1.56
• Storage Temp.: Inert atmosphere,Room Temperature
• Solubility: soluble in Chloroform
• PKA: -1.24±0.20(Predicted)
• CAS DataBase Reference: 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE(102830-75-1)
• EPA Substance Registry System: 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE(102830-75-1)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• HazardClass: IRRITANT
• Hazardous Substances Data: 102830-75-1(Hazardous Substances Data)

Usage

General Description

3-Bromo-5-chloro-2-methoxy-pyridine is a chemical compound with the formula C6H5BrClNO. It is a pyridine derivative that contains bromine, chlorine, and a methoxy group. 3-BROMO-5-CHLORO-2-METHOXY-PYRIDINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Its distinctive structure allows for the introduction of functional groups at the 2-position, making it a valuable building block for organic synthesis. Additionally, 3-Bromo-5-chloro-2-methoxy-pyridine is also used as a reagent in the production of various heterocyclic compounds. Its unique molecular structure and reactivity make it a versatile and important compound in the field of organic chemistry.

InChI:InChI=1/C6H5BrClNO/c1-10-6-5(7)2-4(8)3-9-6/h2-3H,1H3

Upstream product

• 16110-09-1 2,5 dichloropyridine 
• 13473-01-3 5-chloro-2-methoxypyridine 

Downstream Products

• 102830-79-5 (E)-5-chloro-α-<2-(3,4-dichlorophenyl)ethenyl>-2-methoxy-3-pyridinemethanol 
• 102830-86-4 3-(5-Chloro-2-methoxy-3-pyridinyl)-1-(3,4-dichlorophenyl)-propan-1-one 
• 1261451-92-6 5-chloro-2-methoxypyridine-3-sulfonyl chloride 
• 103058-88-4 5-chloro-2-methoxypyridine-3-carboxaldehyde 
• 847345-77-1 5-chloro-2-methoxy-3-phenoxy-pyridine 
• 102830-87-5 4-(5-Chloro-2-methoxy-pyridin-3-yl)-2-(3,4-dichloro-phenyl)-butan-2-ol 
• 103058-95-3 3-(5-Chloro-2-methoxy-pyridin-3-yl)-1-(3,4-dichloro-phenyl)-propan-1-ol 
• 102830-85-3 6-Chloro-2-(3,4-dichlorophenyl)-3,4-dihydro-2-methyl-2H-pyrano<2,3-b>pyridine 
• 102830-88-6 5-Chloro-3-[(E)-3-(3,4-dichloro-phenyl)-but-2-enyl]-2-methoxy-pyridine 
• 106585-00-6 (E)-3-(5-Chloro-2-methoxy-3-pyridinyl)-1-(4-chlorophenyl)-2-propen-1-one 
• 102830-65-9 6-Chloro-2-(3,4-dichlorophenyl)-3,4-dihydro-2H-pyrano<2,3-b>pyridine 
• 102830-83-1 6-Chloro-2-(3,4-dichlorophenyl)-2H-pyrano<2,3-b>pyridine 
• 102830-62-6 6-Chloro-2-(4-chlorophenyl)-3,4-dihydro-2H-pyrano<2,3-b>pyridine 
• 102830-80-8 6-Chloro-2-(4-chlorophenyl)-2H-pyrano<2,3-b>pyridine 

Relevant articles and documents

IMIDAZO [1,2-B] PYRIDAZINE AND IMIDAZO [4,5-B] PYRIDINE DERIVATIVES AS JAK INHIBITORS

New imidazo[1,2-b]pyridazine and imidazo[4,5-b]pyridine derivatives having the chemical structure of formula (I) are disclosed; as well as process for their preparation, pharmaceutical compositions comprising them and their use in therapy as inhibitors of Janus Kinases (JAK).

METHANOANTHRACENEYL METHYL PIPERIDINYL COMPOUNDS

Compounds of formula I or I', STR1 wherein X and Y are independently selected from hydrogen, halo, and (1-6C)alkoxy;R 1 is selected from(A) (1-6C)alkyl; (B) phenyl and naphthyl or substituted versions thereof; (C) phenyl (1-3C)alkyl and naphthyl (1-3C) alkyl;(D) five-and six-membered heteroaryl rings;(E) heteroaryl (1-3C) alkyl and pharmaceutically acceptable salts thereof, useful in the treatment of neuropsychiatric disorders such as psychoses; pharmaceutical compositions comprising a compound of formula I or I' and a pharmaceutically acceptable diluent or carrier; and methods of treating neuropsychiatric disorders comprising administering to a mammal (including man) in need of such treatment an effective amount of a compound of formula I or I', or a pharmaceutically acceptable salt thereof are claimed. The invention also relates to novel processes for producing enantiomeric methanoanthracenyl sulfoxides.

2-phenylpyrano[2,3-b]pyridines and their use in inhibiting viruses

2-Phenylpyrano[2,3-b]pyridines are described herein. These compounds are active against a variety of viruses. A number of procedures can be used to prepare the compounds of this invention but, at some point, they would all make use of the cyclization of a (phenyl) (pyridyl)propanol or (phenyl) (pyridyl)propenol.