1028314-66-0

Basic information

• Product Name: C₂₃H₂₄O₆S₃N₂
• Synonyms: C₂₃H₂₄O₆S₃N₂
• CAS NO: 1028314-66-0
• Molecular Weight: 520.651
• Mol File: 1028314-66-0.mol

Chemical Properties

• CAS DataBase Reference: C₂₃H₂₄O₆S₃N₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₃H₂₄O₆S₃N₂(1028314-66-0)
• EPA Substance Registry System: C₂₃H₂₄O₆S₃N₂(1028314-66-0)

Safety Data

• Hazardous Substances Data: 1028314-66-0(Hazardous Substances Data)

Upstream product

• 933879-61-9 C₉H₁₂O₂SN₂ 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1025992-12-4 C₂₈H₂₅O₃S₂N₃ 

Relevant articles and documents

Synthesis and anti-HIV-1 activity evaluation of 5-alkyl-2-alkylthio-6- (arylcarbonyl or α-cyanoarylmethyl)-3,4-dihydropyrimidin-4(3H)-ones as novel non-nucleoside HIV-1 reverse transcriptase inhibitors

A series of novel S-DABO analogues (S-DABOs, 1) were synthesized and evaluated as inhibitors of human immunodeficiency virus type-1 (HIV-1). Key structural modifications included replacement of the 6-arylmethyl group by a 6-arylcarbonyl or 6-(α-cyanoarylmethyl) group. Most of the compounds showed only micromolar potency against HIV-1 in MT-4 cells in vitro, though two of them (3e and 3g) were unusually potent (IC50 = 0.09 and 0.002 μM, respectively) and selective (SI = 1500 and 4600, respectively). Structure-activity relationships among the newly synthesized S-DABOs are discussed.