102841-46-3

Basic information

• Product Name: Moracin P
• Synonyms: Moracin P;5-[(6R)-6,7-Dihydro-6-hydroxy-7,7-dimethyl-5H-furo[3,2-g][1]benzopyran-2-yl]-1,3-benzenediol
• CAS NO: 102841-46-3
• Molecular Formula: C₁₉H₁₈O₅
• Molecular Weight: 326.34322
• Mol File: 102841-46-3.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 614.3°Cat760mmHg
• Flash Point: 325.3°C
• Appearance: /
• Density: 1.41g/cm³
• Vapor Pressure: 5.99E-16mmHg at 25°C
• Refractive Index: 1.682
• PKA: 9.10±0.10(Predicted)
• CAS DataBase Reference: Moracin P(CAS DataBase Reference)
• NIST Chemistry Reference: Moracin P(102841-46-3)
• EPA Substance Registry System: Moracin P(102841-46-3)

Safety Data

• Hazardous Substances Data: 102841-46-3(Hazardous Substances Data)

Usage

General Description

Moracin P is a natural bioactive chemical compound found in the Morus alba plant, also known as white mulberry. It is a type of flavonoid with antioxidant and anti-inflammatory properties, making it potentially beneficial for various health conditions. Studies have shown that Moracin P has anti-cancer effects and may inhibit the growth of tumor cells. It also has potential applications in treating diabetes, as it can help regulate blood sugar levels and improve insulin sensitivity. Additionally, Moracin P has been found to have neuroprotective effects and could potentially be used in the treatment of neurodegenerative diseases. Overall, the compound shows promise in various areas of health and wellness.

InChI:InChI=1/C19H20O5/c1-19(2)18(22)7-11-3-10-6-15(23-16(10)9-17(11)24-19)12-4-13(20)8-14(21)5-12/h4-6,8-10,18,20-22H,3,7H2,1-2H3

Upstream product

• 102841-43-0 (9R)-moracin P 3'-O-α-L-arabinopyranoside 

Relevant articles and documents

Bioactive benzofuran derivatives from cortex mori radicis, and their neuroprotective and analgesic activities mediated by mGluR1

Four new benzofuran-type stilbene glycosides and 14 known compounds including 8 benzofuran-type stilbenes and 6 flavonoids were isolated from the traditional Chinese medicine, Cortex Mori Radicis. The new compounds were identified as (9R)-moracin P 3′-O-α-L-arabinopyranoside (1), (9R)-moracin P 9-O-β-D-glucopyranoside (2), (9R)-moracin P 3′-O-β-D-glucopyranoside (3), and (9R)-moracin O 10-O-β-D-glucopyranoside (4) based on the spectroscopic interpretation and chemical analysis. Three benzofuran-type stilbenes, moracin O (5), R (7), and P (8) showed significant neuroprotective activity against glutamate-induced cell death in SK-N-SH cells. In addition, moracin O (5) and P (8) also demonstrated a remarkable inhibition of the acetic acid-induced pain. The molecular docking with metabotropic glutamate receptor 1 (mGluR1) results indicated that these neuroprotective benzofuran-type stilbenes might be the active analgesic components of the genus Morus, and acted by mediating the mGluR1 pathway.