1028432-45-2Relevant academic research and scientific papers
Practical approach for preparation of unsymmetric benzils from β-ketoaldehydes
Ruan, Libo,Shi, Min,Li, Nian,Ding, Xu,Yang, Fan,Tang, Jie
, p. 733 - 735 (2014/03/21)
An efficient and practical method for the synthesis of unsymmetric benzils from readily available β-ketoaldehydes has been developed. Various unsymmetric 1,2-diaryldiketones bearing functional groups have been obtained in good to excellent yields under mild reaction conditions. A plausible mechanism was proposed, and α,α-dichloroketone was considered as the key intermediate. The generation of α,α-dichloroketones from β-ketoaldehydes may undergo the following steps: (1) oxidation by sodium hypochlorite, (2) decarboxylation, and (3) chlorination by Cl2 generated from sodium hypochlorite.
Iodine-catalyzed synthesis of 1,2-diaryldiketones by oxidative cleavage of 1,3-diaryldiketones with DMSO
Yuan, Yu,Zhu, Haitao
experimental part, p. 329 - 333 (2012/02/04)
A metal-free, efficient, practical, and convenient process based on an iodine-catalyzed oxidative cleavage reaction has been developed to form 1,2-diaryldiketons in high yields from 1,3-diaryldiketones. The reaction is performed in DMSO and in air, and a mechanism was proposed according to the reaction evidence. Copyright
DMSO-PdI2 as a powerful oxidizing couple of alkynes into benzils: one-pot synthesis of nitrogen-containing five- or six-membered heterocycles
Mousset, Céline,Provot, Olivier,Hamze, Abdallah,Bignon, Jér?me,Brion, Jean-Daniel,Alami, Mouad
, p. 4287 - 4294 (2008/09/19)
PdI2 in DMSO promoted the oxidation of functionalized diarylalkynes into benzil derivatives in excellent yields. This new oxidation reaction was achieved with short reaction times and low loading of palladium catalyst. This efficient catalytic
