1028436-80-7

Basic information

• Product Name: C₃₆H₄₃N₃O₅
• Synonyms: C₃₆H₄₃N₃O₅
• CAS NO: 1028436-80-7
• Molecular Weight: 597.755
• Mol File: 1028436-80-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₆H₄₃N₃O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₆H₄₃N₃O₅(1028436-80-7)
• EPA Substance Registry System: C₃₆H₄₃N₃O₅(1028436-80-7)

Safety Data

• Hazardous Substances Data: 1028436-80-7(Hazardous Substances Data)

Upstream product

• 146737-65-7 1H-indene-2-methanamine, 2,3-dihydro 

Downstream Products

• 1028436-60-3 C₂HF₃O₂*C₃₁H₃₅N₃O₃ 

Relevant articles and documents

Role of benzimidazole (Bid) in the δ-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH2-Bid (UFP-502)

H-Dmt-Tic-NH-CH2-Bid (UFP-502) was the first δ-opioid agonist prepared from the Dmt-Tic pharmacophore. It showed interesting pharmacological properties, such as stimulation of mRNA BDNF expression and antidepression. To evaluate the importance of 1H-benzimidazol-2-yl (Bid) in the induction of δ-agonism, it was substituted by similar heterocycles: The substitution of NH(1) by O or S transforms the reference δ-agonist into δ-antagonists. Phenyl ring of benzimidazole is not important for δ-agonism; in fact 1H-imidazole-2-yl retains δ-agonist activity.