1028570-00-4Relevant academic research and scientific papers
A highly specific BODIPY-based fluorescent probe for the detection of hypochlorous acid
Sun, Zhen-Ning,Liu, Feng-Qin,Chen, Yan,Tam, Paul Kwong Hang,Yang, Dan
, p. 2171 - 2174 (2008)
(Chemical Equation Presented) A fluorescent probe, HKOCl-1, has been successfully developed for the detection of hypochlorous acid on the basis of a specific reaction with p-methoxyphenol. The formation of HOCl has been successfully detected not only in an abiotic system but also in an enzymatic system (myeloperoxidase/H2O2/Cl- system) and in living macrophage cells upon stimulation. This new probe might be used as an efficient tool for probing the roles HOCl plays in biological systems.
