102878-84-2

Basic information

• Product Name: Quinoline-5-sulfonyl Chloride
• Synonyms: Quinoline-5-sulfonyl Chloride;5-Quinolinesulfonyl Chloride
• CAS NO: 102878-84-2
• Molecular Formula: C₉H₆ClNO₂S
• Molecular Weight: 227.66744
• Product Categories: Aromatics;Heterocycles;Sulfonyl Chlorides
• Mol File: 102878-84-2.mol
• Article Data: 6

Chemical Properties

• Melting Point: 91-95 °C
• Boiling Point: 355.9±17.0 °C(Predicted)
• Appearance: /
• Density: 1.483±0.06 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility: Chloroform (Slightly), DMSO (Slightly)
• PKA: 2.21±0.12(Predicted)
• CAS DataBase Reference: Quinoline-5-sulfonyl Chloride(CAS DataBase Reference)
• NIST Chemistry Reference: Quinoline-5-sulfonyl Chloride(102878-84-2)
• EPA Substance Registry System: Quinoline-5-sulfonyl Chloride(102878-84-2)

Safety Data

• Hazardous Substances Data: 102878-84-2(Hazardous Substances Data)

Usage

Uses

Quinoline derivative as antibacterial agents.

Upstream product

• 23261-58-7 quinoline-5-sulfonic acid 
• 611-34-7 5-Aminoquinoline 
• 60999-26-0 5,5'-bisquinolinyl disulfide 
• 3056-03-9 5-mercaptoquinoline 

Downstream Products

• 271247-98-4 (S)-2-benzyloxycarbonyl-3-(N-phenylpiperazin-4-ylcarbonyl)-7-(5-quinolinylsulfonyloxy)-1,2,3,4-tetrahydroisoquinoline 
• 1428128-19-1 sodium 1-(5-chloro-2-((4-chloro-2-fluorobenzyl)oxy)benzyl)-1,2,3,4-tetrahydroquinoline-5-sulfonate 
• 23261-58-7 quinoline-5-sulfonic acid 
• 1155860-39-1 C₂₂H₂₁Cl₂N₃O₃S 
• 415913-05-2 quinoline-5-sulfonamide 
• 109869-21-8 5-benzoylmercapto-1-methyl-quinolinium; methyl sulfate 
• 110334-38-8 5-benzoylmercapto-1-methyl-quinolinium; iodide 
• 127133-87-3 thiobenzoic acid S-[5]quinolyl ester 

Relevant articles and documents

Synthesis, 15N NMR spectra and GIAO calculated data of the seven positional isomers of 15N-labeled N,N-dimethylsulfamoylquinoline

The one-step synthesis of positional isomers of N,N- dimethylsulfamoylquinoline are presented. Seven newly synthesized compounds have been characterized by elemental analyses, MS, 1H and 15N NMR spectral data. The long-range correlations between the ring protons and the endocyclic nitrogen atoms were observed in the gHMBC experiments. The spectral positions of the nitrogen atoms from the sulfonamide groups were drawn from the 1D spectra of the 15N-labeled sulfonamide isotopomers. Correlations between the experimentally determined chemical shifts and GIAO calculated isotropic shielding constants were found. The GIAO calculations were based on HF-, MP2-, and B3LYP-optimized geometries and were performed at the HF, BLYP, and B3LYP levels of theory.

EP1 RECEPTOR LIGANDS

The present invention belongs to the field of EP1 receptor ligands. More specifically it refers to compounds of general formula (I) having great affinity and selectivity for the EP1 receptor. The invention also refers to the process for their preparation, to their use as medicament for the treatment and/or prophylaxis of diseases or disorders mediated by the EP1 receptor as well as to pharmaceutical compositions comprising them.

Identification and optimization of anthranilic sulfonamides as novel, selective cholecystokinin-2 receptor antagonists

A high throughput screening approach to the identification of selective cholecystokinin-2 receptor (CCK-2R) ligands resulted in the discovery of a novel series of antagonists, represented by 1-[2-[(2,1,3-benzothiadiazol-4- ylsulfonyl)amino]-5-chlorobenzoy