102898-91-9

Basic information

• Product Name: HexadecanaMide, N-(4-Methoxyphenyl)-
• Synonyms: HexadecanaMide, N-(4-Methoxyphenyl)-;HEXADECA-P-ANISIDIDE
• CAS NO: 102898-91-9
• Molecular Formula: C₂₃H₃₉NO₂
• Molecular Weight: 361.56126
• Mol File: 102898-91-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: HexadecanaMide, N-(4-Methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: HexadecanaMide, N-(4-Methoxyphenyl)-(102898-91-9)
• EPA Substance Registry System: HexadecanaMide, N-(4-Methoxyphenyl)-(102898-91-9)

Safety Data

• Hazardous Substances Data: 102898-91-9(Hazardous Substances Data)

Upstream product

• 104-94-9 4-methoxy-aniline 
• 57-10-3 1-hexadecylcarboxylic acid 
• 112-67-4 n-hexadecanoyl chloride 

Relevant articles and documents

Synthesis and biological evaluation of new potential inhibitors of N-acylethanolamine hydrolyzing acid amidase

N-Acylethanolamines, including N-palmitoyl-ethanolamine (PEA), are hydrolyzed to the corresponding fatty acids and ethanolamine by fatty acid amide hydrolase (FAAH). Recently, N-acylethanolamine-hydrolyzing acid amidase (NAAA) was identified as being able to specifically hydrolyze PEA. In order to find selective and effective inhibitors of this enzyme, we synthesized and screened several amides, retroamides, esters, retroesters and carbamates of palmitic acid (1-21) and esters with C15 and C17 alkyl chains (22-27). Cyclopentylhexadecanoate (13) exhibited the highest inhibitory activity on NAAA (IC50 = 10.0 μM), without inhibiting FAAH up to 50 μM. Compound 13 may become a useful template to design new NAAA inhibitors.