1028981-50-1

Upstream product

• 59046-72-9 o-(phenylethynyl)benzaldehyde 
• 105-53-3 diethyl malonate 
• 6630-33-7 ortho-bromobenzaldehyde 
• 536-74-3 phenylacetylene 

Downstream Products

• 1028981-64-7 diethyl (Z)-1-benzylidene-3-(1H-indol-1-yl)-1H-indene-2,2(3H)-dicarboxylate 
• 1028981-87-4 3,3'-((2-(phenylethynyl)phenyl)methylene)bis(1H-indole) 
• 1028981-93-2 C₃₀H₂₇NO₄ 
• 1028981-66-9 diethyl (Z)-1-benzylidene-3-(5-bromo-1H-indol-1-yl)-1H-indene-2,2(3H)-dicarboxylate 
• 1028981-89-6 3,3'-((2-(phenylethynyl)phenyl)methylene)bis(5-bromo-1H-indole) 
• 1028981-70-5 diethyl (Z)-1-benzylidene-3-(6-methoxy-1H-indol-1-yl)-1H-indene-2,2(3H)-dicarboxylate 
• 1028981-68-1 diethyl (Z)-1-benzylidene-3-(4-methoxy-1H-indol-1-yl)-1H-indene-2,2(3H)-dicarboxylate 
• 1192649-92-5 diethyl 2-(3-bromo-2-phenyl-1H-inden-1-ylidene)malonate 
• 1258791-02-4 (Z)-diethyl 1-benzylidene-3-(1H-imidazol-1-yl)-1H-indene-2,2(3H)-dicarboxylate 
• 1258791-03-5 (Z)-diethyl 1-(1H-benzo[d]imidazol-1-yl)-3-benzylidene-1H-indene-2,2(3H)-dicarboxylate 
• 1258791-05-7 (Z)-diethyl 1-benzylidene-3-(1H-naphtho[2,3-d]imidazol-1-yl)-1H-indene-2,2(3H)-dicarboxylate 
• 1258791-04-6 (Z)-diethyl 1-benzylidene-3-(5-methyl-1H-benzo[d]imidazol-1-yl)-1H-indene-2,2(3H)-dicarboxylate 

Relevant academic research and scientific papers

Domino hydroarylation-cyclization reaction: One-pot synthesis of indane-fused 3,4-dihydrocoumarins

A tin(II) triflate-catalyzed domino hydroarylation-cyclization reaction has been developed to access a wide-variety of methyleneindane-fused 3,4-hydrocoumarins. A judiciously selected bi-functional Lewis acidic catalyst has been successfully applied to promote two ring-closing events as a single-pot operation.

Sc(OTf)3-catalyzed or t-BuOK promoted tandem reaction of 2-(2-(alkynyl)benzylidene)malonate with indole

(Chemical Equation Presented) Tandem reaction of 2-(2-(alkynyl)benzylidene) malonate with indole was investigated. (Z)-1-Benzylidene-3-(1H-indol-1-yl)-1H- indene-2,2(3H)-dicarboxylate was generated in the presence of t-BuOK at room temperature; whereas 3-((1H-indol-3-yl)(2-(alkynyl)aryl)methyl)-1H-indole was obtained when Sc(OTf)3 was utilized as catalyst at 50°C.