1029017-63-7

Basic information

• Product Name: N'-(4-hydroxy-3-methoxybenzylidene)-2-pyrazinecarbohydrazide
• Synonyms: N'-(4-hydroxy-3-methoxybenzylidene)-2-pyrazinecarbohydrazide
• CAS NO: 1029017-63-7
• Molecular Formula: C13H12N4O3
• Molecular Weight: 272.25938
• Mol File: 1029017-63-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N'-(4-hydroxy-3-methoxybenzylidene)-2-pyrazinecarbohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: N'-(4-hydroxy-3-methoxybenzylidene)-2-pyrazinecarbohydrazide(1029017-63-7)
• EPA Substance Registry System: N'-(4-hydroxy-3-methoxybenzylidene)-2-pyrazinecarbohydrazide(1029017-63-7)

Safety Data

• Hazardous Substances Data: 1029017-63-7(Hazardous Substances Data)

Upstream product

• 768-05-8 pyrazine-2-carbohydrazide 
• 121-33-5 vanillin 
• 6164-79-0 methyl pyrazine-2-carboxylate 
• 98-97-5 2-pyrazylcarboxylic acid 

Relevant articles and documents

Synthesis andanti-mycobacterial evaluation of some pyrazine-2-carboxylic acid hydrazide derivatives

A series of pyrazine-2-carboxylic acid hydrazide derivatives were synthesized and screened for their activity against Mycobacterium tuberculosis. The results show that pyrazine-2-carboxylic acid hydrazi-deehydrazone derivatives 3ael were less active than pyrazinamide. In contrast,the N 4-ethyl-N1-pyr-azinoyl-thiosemicarbazide 4 showed the highest activity against M. tuberculosis H37Rv (IC90 16.87 mg/mL). Details of the structureeactivity and structureecytotoxicity relationships are discussed.

Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates

In this paper, we report the synthesis and pharmacological evaluation of pyrazine N-acylhydrazone (NAH) derivatives (2a-s) designed as novel analgesic and anti-inflammatory drug candidates. This series was planned by molecular simplification of prototype