1029095-92-8Relevant articles and documents
Stereoselective synthesis of 3,3-diarylacrylonitriles as tubulin polymerization inhibitors
Fang, Zhenglai,Song, Yunlong,Sarkar, Taradas,Hamel, Ernest,Fogler, William E.,Agoston, Gregory E.,Fanwick, Phillip E.,Cushman, Mark
, p. 4241 - 4244 (2008/09/20)
(Chemical Equation Presented) A series of 3,3-diarylacrylonitriles were synthesized stereo-selectively as tubulin polymerization inhibitors for potential use in cancer chemotherapy. This synthetic route features stannylcupration and palladium-catalyzed St