102936-57-2

Basic information

• Product Name: CYCLOPENTYL-THIOUREA
• Synonyms: N-CYCLOPENTYLTHIOUREA;CYCLOPENTYL-THIOUREA
• CAS NO: 102936-57-2
• Molecular Formula: C₆H₁₂N₂S
• Molecular Weight: 144.24
• Mol File: 102936-57-2.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 241.1°Cat760mmHg
• Flash Point: 99.6°C
• Appearance: /
• Density: 1.13g/cm³
• Vapor Pressure: 0.0366mmHg at 25°C
• Refractive Index: 1.579
• CAS DataBase Reference: CYCLOPENTYL-THIOUREA(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOPENTYL-THIOUREA(102936-57-2)
• EPA Substance Registry System: CYCLOPENTYL-THIOUREA(102936-57-2)

Safety Data

• Hazardous Substances Data: 102936-57-2(Hazardous Substances Data)

Usage

Description

Cyclopentyl-thiourea, with the molecular formula C6H11NS, is a thiourea derivative that serves as a key component in the synthesis of pharmaceuticals and agrochemicals. It is recognized for its stability and low toxicity, making it a valuable compound in various industrial applications.

Uses

Used in Pharmaceutical and Agrochemical Industries:
Cyclopentyl-thiourea is utilized as a building block in the synthesis of various pharmaceuticals and agrochemicals, contributing to the development of new drugs and pesticides.
Used in Polymer Production:
CYCLOPENTYL-THIOUREA functions as a catalyst in the production of polymers, playing a crucial role in the manufacturing process to ensure the desired properties of the final product.
Used as an Industrial Stabilizer:
Cyclopentyl-thiourea is employed as a stabilizer for certain industrial products, helping to maintain their quality and performance over time.
Used in Research and Development:
In the realm of research and development, cyclopentyl-thiourea serves as a reagent for the detection and analysis of specific organic compounds, aiding scientists in their studies and discoveries.

InChI:InChI=1/C6H12N2S/c7-6(9)8-5-3-1-2-4-5/h5H,1-4H2,(H3,7,8,9)

Upstream product

• 1003-03-8 Cyclopentamine 
• 33522-03-1 cyclopentyl isothiocyanate 
• 70498-31-6 N-tert-butyl-N'-cyclopentyl thiourea 

Downstream Products

• 1505452-78-7 3-cyclopentyl-2-imino-5,5-bis(4-methoxyphenyl)imidazolidin-4-one 
• 860344-65-6 4-(2-cyclopentylamino-thiazol-4-yl)-benzoic acid 

Relevant articles and documents

Synthesis method of 2-aminothiazole pyrimidine serving as CDK2 inhibitor

The invention relates to the technical field of organic synthesis and medicines, and particularly discloses a synthesis method of 2-aminothiazole pyrimidine serving as a CDK/2 inhibitor. The synthesismethod comprises the following steps: converting amino into isothiocyanate, reacting the isothiocyanate with primary amine to generate thiourea, and carrying out Hantzsch thiazole synthesis reaction,fluorination reaction and condensation of enaminone and guanidine hydrochloride to form a pyrimidine ring. According to the method, through five steps of reactions, the total yield reaches 35%-48%. The method has the advantages that a traditional fluorination method is replaced by photocatalysis; the yield of the whole process is greatly increased, the yield is increased to 85% from 35% through the fluorination reaction, and compared with a traditional fluorination method in a low-temperature ice salt bath, the method is milder in condition, only needs to be carried out at the room temperature, and is a good process for synthesizing the CDK/2 inhibitor 2-aminothiazole pyrimidine.

COMPOSITIONS AND METHODS FOR THE TREATMENT OF MALARIA

The present invention provides aminohydantoin anti-malarial agents. In some embodiments, these agents have the property of functions of targeting malarial aspartic proteases while at the same time having low activity against human BACE. Methods of employing such agents are also provided.

CYSTEINE PROTEASE INHIBITORS

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