1029435-63-9Relevant academic research and scientific papers
Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1)
Bell, Mark,Foley, David,Naylor, Claire,Wood, Gavin,Robinson, Colin,Riley, Jennifer,Epemolu, Ola,Ellis, Lucy,Scullion, Paul,Shishikura, Yoko,Osuna-Cabello, Maria,Ferguson, Liam,Pinto, Erika,Fletcher, Daniel,Katz, Elad,McLean, W. H. Irwin,Wyatt, Paul,Read, Kevin D,Woodland, Andrew
, p. 341 - 347 (2019)
In order to study the role of S1PRs in inflammatory skin disease, S1PR modulators are dosed orally and topically in animal models of disease. The topical application of S1PR modulators in these models may, however, lead to systemic drug concentrations, wh
NEW PROCESS FOR THE PREPARATION OF 2-IMINO-THIAZOLIDIN-4-ONE DERIVATIVES
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Page/Page column 19; 24; 26, (2008/12/05)
The present invention relates to a new process for the preparation of 2-imino- thiazolidin-4-one compounds of the Formula (I) and (II) and to compounds of Formula (II) as such. The present compounds of Formula (II) can be used as intermediates in the preparation of thiazolidin-4-one derivatives of the General Formula (II), said derivatives being described in WO 2005/054215. These compounds of General Formula (II) are described in WO 2005/054215 to act as immunosuppressive agents.
