1029548-00-2Relevant academic research and scientific papers
Effect of aromatic substitution on antimuscarinic activity of 2-phenyl- 2-cyclohexyl-4-[(dimethylamino)methyl]-1,3-dioxolanes
Angeli, Piero,Brasili, Livio,Franchini, Silvia,Giardina, Dario,Gulini, Ugo,Marucci, Gabriella
, p. 89 - 97 (2007/10/03)
A series of 2-substituted 1,3-dioxolane ligands were synthesized and tested as muscarinic antagonists. The compounds display moderate to high affinity for the three receptor subtypes M1-M3, with some of them showing a modest selectiv
