1029692-15-6 Usage
General Description
Isopropyl (2S)-7-Cyano-4-(pyridin-2-ylmethyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-2-ylcarbamate, also known as Apatinib, is a chemical compound that belongs to the class of indole derivatives. It is a selective VEGFR-2 inhibitor that has been investigated for its potential in cancer treatment, particularly in advanced gastric and gastroesophageal junction adenocarcinoma. Apatinib works by inhibiting the activity of vascular endothelial growth factor receptor 2 (VEGFR-2), which plays a crucial role in tumor angiogenesis. As a result, it may help prevent the growth and spread of cancer cells by cutting off their blood supply. Apatinib has shown promise in clinical trials and is being studied for its potential as a targeted therapy for various types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 1029692-15-6 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,2,9,6,9 and 2 respectively; the second part has 2 digits, 1 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1029692-15:
(9*1)+(8*0)+(7*2)+(6*9)+(5*6)+(4*9)+(3*2)+(2*1)+(1*5)=156
156 % 10 = 6
So 1029692-15-6 is a valid CAS Registry Number.
1029692-15-6Relevant articles and documents
TREATMENT OF ANDROGEN DEPRIVATION THERAPY ASSOCIATED SYMPTOMS
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, (2017/07/14)
The present invention provides a method of treating symptoms associated with Androgen Deprivation Therapy comprising administering to a patient in need of such treatment an effective amount of a compound of Formula I: [Formula should be inserted here] or a pharmaceutically acceptable salt thereof.