1029693-99-9Relevant academic research and scientific papers
Design and synthesis of planar chiral heterocyclic carbene precursors derived from [2.2]paracyclophane
Duan, Wenzeng,Ma, Yudao,Xia, Houqi,Liu, Xueying,Ma, Qingshuang,Sun, Junshan
, p. 4330 - 4333 (2008/09/21)
(Chemical Equation Presented) A unique family of planar chiral symmetrical N-heterocyclic carbene precursors with restricted flexibility derived from [2.2]paracyclopane were obtained by a new synthetic route. The resolution of 4-amino-13-bromo[2.2]paracyclophane was achieved with relatively high efficiency. Starting from (45p,13Rp)-4-amino-13-bromo[2.2] paracyclophane, the planar chiral pseudogem-disubstituted [2.2]paracyclophanyl dihydroimidazoliums were prepared in a four-step sequence with good yields. The resulting dihydroimidazolium salts were fully characterized with a series of methods including single-crystal X-ray diffraction technique.
