102970-91-2Relevant academic research and scientific papers
GRIGNARD REAGENT INDUCED SELF-CONDENSATION OF BENZOXAZOLES: SYNTHESIS OF BENZOXAZOLYLALKYL ALKYL KETONES.
Florio, Saverio,Ingrosso, Giovanni,Sgarra, Riccardo
, p. 3091 - 3094 (2007/10/02)
2-Alkylbenzoxazoles 1 undergo clean Claisen-type self-condensation upon treatment with n-BuMgBr and quenching with aqueous NH4Cl to give 5.In contrast, quenching of the reaction with aqueous HCl furnishes quite good yields of the benzoxazolylalkyl alkyl ketones 8.
