1029773-05-4

Basic information

• Product Name: 2-(4-Fluoro-phenyl)-quinolin-7-ylamine
• Synonyms: 7-amino-2-(4-fluorophenyl)quinoline;2-(4-Fluoro-phenyl)-quinolin-7-ylamine
• CAS NO: 1029773-05-4
• Molecular Formula: C₁₅H₁₁FN₂
• Molecular Weight: 238.2596432
• Mol File: 1029773-05-4.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(4-Fluoro-phenyl)-quinolin-7-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-Fluoro-phenyl)-quinolin-7-ylamine(1029773-05-4)
• EPA Substance Registry System: 2-(4-Fluoro-phenyl)-quinolin-7-ylamine(1029773-05-4)

Safety Data

• Hazardous Substances Data: 1029773-05-4(Hazardous Substances Data)

Upstream product

• 98276-57-4 2,4-Diamino-benzaldehyde 
• 459-57-4 4-fluorobenzaldehyde 

Relevant articles and documents

TAU IMAGING PROBE

An object of the present invention is to provide a probe for imaging a β-sheet structure protein which can be used for the diagnosis of conformational diseases, particularly disease (tauopathy) having a cardinal symptom such as intracerebral accumulation of tau protein, for example, Alzheimer's disease. Another object of the present invention is to provide a compound which is highly specific to tau and can image tau with satisfactory sensitivity, and also has high brain transition, low or non-recognized bone-seeking properties and low or non-recognized toxicity. According to the present invention, the above problems are solved by providing a compound of a formula I (wherein A, R1, R2, R3, R4, R5, R6, Ra and Rb are as defined in the present description) or a pharmaceutically acceptable salt or solvate thereof.