10299-49-7Relevant articles and documents
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Detzer,Huber
, p. 1937,1938,1940 (1975)
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Cyanide mediated decarboxylation of 1-substituted-4-oxoquinoline and 4-oxo-1,8-naphthyridine-3-carboxylic acids
Reuman, Michael,Eissenstat, Michael A.,Weaver III, John D.
, p. 8303 - 8306 (1994)
Electron deficient 3-quinolinecarboxylic acids undergo ready decarboxylation in the presence of cyanide ion. This reaction most likely requires the addition of CN- to the 2-position of the quinoline (or naphthyridine) nucleus to provide a β-keto acid intermediate that rapidly decarboxylates to give the 3-H substituted product.