103040-92-2

Basic information

• Product Name: 5-Benzothiazolecarboxylicacid,2-amino-,ethylester(6CI,9CI)
• Synonyms: 5-Benzothiazolecarboxylicacid,2-amino-,ethylester(6CI,9CI)
• CAS NO: 103040-92-2
• Molecular Formula: C₁₀H₁₀N₂O₂S
• Molecular Weight: 222.27
• Product Categories: BENZOTHIAZOLE
• Mol File: 103040-92-2.mol

Chemical Properties

• Melting Point: 236-238 °C
• Boiling Point: 386.8±34.0 °C(Predicted)
• Appearance: /
• Density: 1.364±0.06 g/cm3(Predicted)
• PKA: 3.04±0.10(Predicted)
• CAS DataBase Reference: 5-Benzothiazolecarboxylicacid,2-amino-,ethylester(6CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzothiazolecarboxylicacid,2-amino-,ethylester(6CI,9CI)(103040-92-2)
• EPA Substance Registry System: 5-Benzothiazolecarboxylicacid,2-amino-,ethylester(6CI,9CI)(103040-92-2)

Safety Data

• Hazardous Substances Data: 103040-92-2(Hazardous Substances Data)

Upstream product

• 103261-70-7 ethyl benzo[d]thiazole-5-carboxylate 
• 3425-46-5 potassium selenocyanate 
• 19045-66-0 thiocarbamic acid 
• 5798-75-4 Ethyl 4-bromobenzoate 
• 20967-87-7 3-[(aminothioxomethyl)amino]benzoic acid ethyl ester 
• 582-33-2 3-aminobenzoic acid ethyl ester 

Relevant articles and documents

Iodine-catalyzed amination of benzothiazoles with KSeCN in water to access primary 2-aminobenzothiazoles

A facile and sustainable approach for the amination of benzothiazoles with KSeCN using iodine as the catalyst in water has been disclosed under transition-metal free conditions. The reaction proceeded smoothly to afford various primary 2-amino benzothiazoles in up to 96% yield. A series of control experiments were performed, suggesting a ring-opening mechanism was involved via a radical process. This protocol provides efficient synthesis of primary 2-aminobenzothiazoles

ANTIBIOTIC COMPOUNDS, PHARMACEUTICAL FORMULATIONS THEREOF AND METHODS AND USES THEREFOR

The present invention relates to compounds of formula (I) wherein G1 to G8 are as defined herein. The compounds are PK inhibitors and as such represent a new approach to treating pathogenic infections, including multidrug resistant pathogens. Disclosed herein are the compounds of formula (I), pharmaceutical compositions comprising the compounds of formula (I) and their use in the treatment of antimicrobial infection. (Formula (1))

Electrochemical intramolecular c-h amination: Synthesis of benzoxazoles and benzothiazoles

A new method for metal-free intramolecular C-H amination has been developed. Electrochemical oxidation of 2-pyrimidyloxybenzenes and 2-pyrimidylthiobenzenes, which can be easily prepared from phenols and thiophenols, respectively, followed by the treatment of the resulting pyrimidinium ions with piperidine gives 2-aminobenzoxazoles and 2-aminobenzothiazoles, respectively.

HETEROCYCLE-SUBSTITUTED BICYCLIC AZOLE PESTICIDES

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, and A, R1, m, X1, X2, X3, X4, Y1, Y2 and Y3 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound or a composition of the invention.

INDAZOLES, BENZOTHIAZOLES, AND BENZOISOTHIAZOLES, AND PREPARATION AND USES THEREOF

The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds (indazoles and benzothiazoles), which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.