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Upstream product

• 145626-28-4 (2E)-3-(2,5-dimethoxyphenyl)-1-(2-hydroxyphenyl)prop-2-en-1-one 
• 95-54-5 1,2-diamino-benzene 
• 5452-99-3 2'-hydroxy-2,5-dimethoxychalcone 

Relevant academic research and scientific papers

Synthesis of 1,5-benzodiazepines with unusual substitution pattern from chalcones under solvent-free microwave irradiation conditions

1,5-Benzodiazepines have been synthesized from the corresponding 2'-hydroxychalcones [1-(2-hydroxyphenyl)-3-aryl-2-propen-1-ones] and o-phenylenediamine, both in methanol, under reflux and under solvent-free microwave irradiation conditions on alumina. Th

4-(2-Hydroxy-phen-yl)-2-phenyl-2,3-dihydro-1H-1,5-benzodiazepine and the 2-(2,3-dimethoxy-phen-yl)-, 2-(3,4-dimethoxy-phen-yl)- and 2-(2,5-dimeth-oxy- phen-yl)-substituted derivatives

The 1,5-benzodiazepine ring system exhibits a puckered boat-like conformation for all four title compounds [4-(2-hydroxy-phen-yl)-2-phenyl-2,3- dihydro-1H-1,5-benzodiazepine, C21H18N2O, (I), 2-(2,3-dimethoxy-phen-yl)-4-(2- hydroxy-phen-yl)-2,3-dihydro-1H-