1030623-56-3

Basic information

• Product Name: 4-{[(tert-butyldiphenylsilyl)oxy]methyl}piperidine
• Synonyms: 4-{[(tert-butyldiphenylsilyl)oxy]methyl}piperidine
• CAS NO: 1030623-56-3
• Molecular Weight: 353.58
• Mol File: 1030623-56-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 4-{[(tert-butyldiphenylsilyl)oxy]methyl}piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{[(tert-butyldiphenylsilyl)oxy]methyl}piperidine(1030623-56-3)
• EPA Substance Registry System: 4-{[(tert-butyldiphenylsilyl)oxy]methyl}piperidine(1030623-56-3)

Safety Data

• Hazardous Substances Data: 1030623-56-3(Hazardous Substances Data)

Upstream product

• 6457-49-4 4-piperidinemethanol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1030623-57-4 2-[4-({[tert-butyl(diphenyl)silyl]oxy}methyl)piperidin-1-yl]-2-oxoethyl acetate 
• 1030623-62-1 3-[4-({[tert-butyl(diphenyl)silyl]oxy}methyl)piperidin-1-yl]propyl acetate 

Relevant articles and documents

A general method for the direct transformation of common tertiary amides into ketones and amines by addition of Grignard reagents

The direct transformation of amides into ketones by addition of organometallic reagents has attracted the attention of organic chemists for a long time. However limited methods are reliable for common amides and have found synthetic applications. Here we report a method featuring in situ activation of tertiary amides with triflic anhydride (Tf2O) followed by addition of Grignard reagents. The method displays a good generality in scope for both amides and Grignard reagents, and it can be viewed as the acylation of Grignard reagents using amides as stable and selective acylating agents. Moreover, this deaminative alkylation reaction provides a mild method for the N-Deacylation of amides to give free amines.

1H-PYRROLE-2,5-DIONE COMPOUNDS AND METHODS OF USING THEM TO INDUCE SELF-RENEWAL OF STEM/PROGENITOR SUPPORTING CELLS

The present invention relates to 1H-pyrrole-2,5-dione compounds and methods of using them to induce self-renewal of stem/progenitor supporting cells, including inducing the stem/progenitor cells to proliferate while maintaining, in the daughter cells, the capacity to differentiate into tissue cells.

CYCLICALLY SUBSTITUTED 3,5-DICYANO-2-THIOPYRIDINES AND USE THEREOF

The present application relates to novel 4-cycloalkyl- and 4-heterocycloalkyl-3,5-dicyano-2-thio-pyridine derivatives, to processes for their preparation, to their use for the treatment and/or prophylaxis of diseases and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, preferably for the treatment and/or prevention of hypertension and other cardiovascular disorders.