1030828-96-6

Basic information

• Product Name: 5-(4-(benzyloxy)phenyl)isoxazol-3-ol
• Synonyms: 5-(4-(benzyloxy)phenyl)isoxazol-3-ol
• CAS NO: 1030828-96-6
• Molecular Formula: C₁₆H₁₃NO₃
• Molecular Weight: 267.27932
• Mol File: 1030828-96-6.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(4-(benzyloxy)phenyl)isoxazol-3-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-(benzyloxy)phenyl)isoxazol-3-ol(1030828-96-6)
• EPA Substance Registry System: 5-(4-(benzyloxy)phenyl)isoxazol-3-ol(1030828-96-6)

Safety Data

• Hazardous Substances Data: 1030828-96-6(Hazardous Substances Data)

Usage

Compound type

Isoxazol-3-ol derivative

Substituents

Benzyl ether group attached to phenyl ring

Potential applications

Medicinal chemistry, drug development

Pharmacological properties

Interesting bioactive potential

Chemical reactivity

Enhanced by benzyl ether group

Therapeutic potential

Further research may reveal uses in medical conditions

Upstream product

• 1030829-56-1 ethyl 3-[4-(benzyloxy)phenyl]prop-2-ynoate 
• 540-38-5 p-Iodophenol 
• 1030828-84-2 3-(4-chlorophenyl)-2-propionic acid ethyl ester 
• 100-39-0 benzyl bromide 
• 19578-68-8 4-(4-benzyloxyphenyl) iodide 

Downstream Products

• 1030828-97-7 5-[4-(benzyloxy)phenyl]-3-(methoxymethoxy)-1,2-oxazole 
• 1030829-57-2 5-(4-(benzyloxy)phenyl)isoxazol-3-yl pivalate 
• 1030828-94-4 4-[3-(methoxymethoxy)-1,2-oxazol-5-yl]phenol 
• 1198744-18-1 5-(4-(2-(3-isopropoxyphenyl)propoxy)phenyl)-isoxazol-3-ol 
• 1198745-10-6 1-{3-[(1-methylethyl)oxy]phenyl}-2-{[4-(3-{[(methyloxy)methyl]oxy} isoxazol-5-yl)phenyl]oxy}ethanone 
• 1198745-11-7 1-{3-[(1-methylethyl)oxy]phenyl}-2-{[4-(3-{[(methyloxy)methyl]oxy}isoxazol-5-yl)phenyl]oxy}ethanol 
• 1198745-12-8 5-{4-[(2-fluoro-2-{3-[(1-methylethyl)oxy]phenyl}ethyl)oxy]phenyl}-3-{[(methyloxy)methyl]oxy}isoxazole 
• 1198745-21-9 5-(4-{[1-(3-isopropoxyphenyl)ethoxy]methyl}phenyl)-3-(methoxymethoxy)isoxazole 
• 1198744-87-4 2-((1-methylethyl)oxy)-4-(2-((4-(3-(((methyloxy)methyl)oxy)isoxazol-5-yl)phenyl)oxy)propyl)pyridine 
• 1198744-88-5 2-((1-methylethyl)oxy)-4-((2S)-2-((4-(3-(((methyloxy)methyl)oxy)isoxazol-5-yl)phenyl)oxy)propyl)pyridine 
• 1198744-89-6 2-((1-methylethyl)oxy)-4-((2R)-2-((4-(3-(((methyloxy)methyl)oxy)isoxazol-5-yl)phenyl)oxy)propyl)pyridine 
• 1198744-80-7 5-(4-(((1S)-1-methyl-2-(2-((1-methylethyl)oxy)pyridin-4-yl)ethyl)oxy)phenyl)isoxazol-3-ol sodium salt 

Relevant articles and documents

HYDROXY ISOXAZOLE COMPOUNDS USEFUL AS GPR120 AGONISTS

The present invention relates to a compound represented by formula (I) : and pharmaceutically acceptable salts thereof are disclosed as useful for treating or preventing diabetes, hyperlipidemia, obesity, NASH, inflammation related disorders, and related diseases and conditions. The compounds are useful as agonists of the G-protein coupled receptor GPR120. Pharmaceutical compositions and methods of treatment are also included.

NOVEL PHENYL-ISOXAZOL-3-OL DERIVATIVE

The present invention relates to a compound represented by formula (I), which has a GPR120 agonist action and thus is useful for treatment of diabetes mellitus or hyperlipidemia, or a pharmaceutically acceptable salt thereof. In the formula, (AA) represents a phenyl or the like, which may be substituted with a lower alkoxy group or the like; (BB) represents a divalent group or the like, derived by removal of two hydrogen atoms from a benzene which may be substituted with a halogen atom or the like; X represents a spacer having a main chain composed of 1-8 carbon atoms wherein 1-3 carbon atoms in the main chain may be substituted with an oxygen atom or the like; and Y represents a hydrogen atom or the like.