1030829-74-3Relevant academic research and scientific papers
A novel chiral (salen)AlIII complex catalyzed asymmetric cyanosilylation of aldehydes
Zeng, Zebing,Zhao, Guofeng,Zhou, Zhenghong,Tang, Chuchi
, p. 1615 - 1618 (2008)
A novel chiral (salen)AlIII complex was synthesized through the reaction of Et2AlCl and salen (R,R)-1 derived from (R,R)-11,12-diamino-9,10-dihydro-9,10-ethanoanthracene. This complex is an efficient catalyst for the asymmetric trimethylsilylcyanation of aldehydes in the presence of tributylphosphane oxide as an additive. The use of 1 mol-% of the complex led to the corresponding cyanohydrins in high yields (85-94%) with good-to-excellent enantioselectivities (42-92%ee). Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
