1030849-86-5Relevant academic research and scientific papers
Development of 2-tbutyl-N-methyl pyrimidones as potent inhibitors of HIV integrase
Di Francesco, M. Emilia,Pace, Paola,Fiore, Fabrizio,Naimo, Francesca,Bonelli, Fabio,Rowley, Michael,Summa, Vincenzo
, p. 2709 - 2713 (2008/12/21)
A series of novel 2-tbutyl-N-methyl pyrimidone HIV-1 integrase inhibitors have been identified. Optimization of the initial lead resulted in compounds such as 9d and 14a, which showed high levels of activity in cell culture inhibiting viral rep
