1030899-00-3Relevant academic research and scientific papers
Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives
Asano, Moriteru,Hitaka, Takenori,Imada, Takashi,Yamada, Masami,Morimoto, Megumi,Shinohara, Hiromi,Hara, Takahito,Yamaoka, Masuo,Santou, Takashi,Nakayama, Masaharu,Imai, Yumi,Habuka, Noriyuki,Yano, Jason,Wilson, Keith,Fujita, Hisashi,Hasuoka, Atsushi
, p. 1897 - 1901 (2017/04/10)
We recently reported a class of novel tissue-selective androgen receptor modulators (SARMs), represented by a naphthalene derivative A. However, their pharmacokinetic (PK) profiles were poor due to low metabolic stability. To improve the PK profiles, we m
