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1H-Pyrazol-4-amine, 5-methyl-1-phenyl-, also known as 5-methyl-1-phenyl-1H-pyrazole-4-amine, is a chemical compound with the molecular formula C10H11N3. It is a derivative of pyrazole, featuring an amine functional group, a methyl group, and a phenyl substituent. 1H-Pyrazol-4-amine, 5-methyl-1-phenylhas been studied for its potential pharmaceutical applications, such as serving as a building block in the synthesis of organic compounds or as a starting material in the development of new drugs. It may also have potential industrial applications in the manufacturing of various products. However, due to its potential reactivity and toxicity, it is important to handle 1H-Pyrazol-4-amine, 5-methyl-1-phenyl- with care.

103095-52-9

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103095-52-9 Usage

Uses

Used in Pharmaceutical Industry:
1H-Pyrazol-4-amine, 5-methyl-1-phenylis used as a building block in the synthesis of organic compounds for the development of new drugs. Its unique structure and functional groups make it a promising candidate for the creation of pharmaceutical agents with potential therapeutic applications.
Used in Chemical Synthesis:
1H-Pyrazol-4-amine, 5-methyl-1-phenylis used as a starting material in the development of new chemical compounds. Its versatile structure allows for further functionalization and modification, enabling the synthesis of a wide range of organic molecules with various properties and applications.
Used in Industrial Applications:
1H-Pyrazol-4-amine, 5-methyl-1-phenylmay have potential applications in the manufacturing of various products in the industrial sector. Its unique chemical properties and reactivity could be harnessed for the production of specialty chemicals, materials, or other industrial products.

Check Digit Verification of cas no

The CAS Registry Mumber 103095-52-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,0,9 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 103095-52:
(8*1)+(7*0)+(6*3)+(5*0)+(4*9)+(3*5)+(2*5)+(1*2)=89
89 % 10 = 9
So 103095-52-9 is a valid CAS Registry Number.

103095-52-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-methyl-1-phenylpyrazol-4-amine

1.2 Other means of identification

Product number -
Other names 5-methyl-1-phenyl-1H-pyrazol-4-ylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:103095-52-9 SDS

103095-52-9Downstream Products

103095-52-9Relevant academic research and scientific papers

Depsipeptides Featuring a Neutral P1 Are Potent Inhibitors of Kallikrein-Related Peptidase 6 with On-Target Cellular Activity

De Vita, Elena,Schüler, Peter,Lovell, Scott,Lohbeck, Jasmin,Kullmann, Sven,Rabinovich, Eitan,Sananes, Amiram,He?ling, Bernd,Hamon, Veronique,Papo, Niv,Hess, Jochen,Tate, Edward W.,Gunkel, Nikolas,Miller, Aubry K.

supporting information, p. 8859 - 8874 (2018/10/09)

Kallikrein-related peptidase 6 (KLK6) is a secreted serine protease that belongs to the family of tissue kallikreins (KLKs). Many KLKs are investigated as potential biomarkers for cancer as well as therapeutic drug targets for a number of pathologies. KLK6, in particular, has been implicated in neurodegenerative diseases and cancer, but target validation has been hampered by a lack of selective inhibitors. This work introduces a class of depsipeptidic KLK6 inhibitors, discovered via high-throughput screening, which were found to function as substrate mimics that transiently acylate the catalytic serine of KLK6. Detailed structure-activity relationship studies, aided by in silico modeling, uncovered strict structural requirements for potency, stability, and acyl-enzyme complex half-life. An optimized scaffold, DKFZ-251, demonstrated good selectivity for KLK6 compared to other KLKs, and on-target activity in a cellular assay. Moreover, DKFZ-633, an inhibitor-derived activity-based probe, could be used to pull down active endogenous KLK6.

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