1031-92-1

Basic information

• Product Name: Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-, dihydrochloride
• Synonyms: 1-(4-Chlorobenzhydryl)piperazine dihydrochloride;1-(p-Chloro-alpha-phenylbenzyl)piperazine dihydrochloride;N-(4-Chlorobenzhydryl)piperazine dihydrochloride;N-(p-Chlorobenzhydryl)piperazine dihydrochloride;Norchlorcyclizine dihydrochloride;Norchlorcyclizine HCl;Piperazine, 1-((4-chlorophenyl)phenylmethyl)-, dihydrochloride;Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-, dihydrochloride
• CAS NO: 1031-92-1
• Molecular Formula: C17H21Cl3N2
• Molecular Weight: 359.72104
• Mol File: 1031-92-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 409.1°Cat760mmHg
• Flash Point: 193.3°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 6.66E-07mmHg at 25°C
• CAS DataBase Reference: Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-, dihydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-, dihydrochloride(1031-92-1)
• EPA Substance Registry System: Piperazine, 1-(p-chloro-alpha-phenylbenzyl)-, dihydrochloride(1031-92-1)

Safety Data

• Hazardous Substances Data: 1031-92-1(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H19ClN2.2ClH/c18-16-8-6-15(7-9-16)17(14-4-2-1-3-5-14)20-12-10-19-11-13-20;;/h1-9,17,19H,10-13H2;2*1H

Upstream product

• 454217-55-1 1-[(4-chlorophenyl)phenylmethyl]-4-(tert-butoxycarbonyl)-piperazine 
• 303-26-4 N-(4-chlorobenzhydryl)piperazine 

Relevant articles and documents

OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES

The present invention is related to l-[(4-chlorophenyl)-phenylmethyl]-4-(2,2,2-trichloroethoxycarbonyl)-piperazine of the Formula (IV) and optically isomers thereof, process for preparation thereof and the use of the compound of the Formula (IV) in the preparation of l-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers and salts thereof. l-(4-chlorophenyl)-phenylmethyl-piperazine and optical isomers thereof are important intermediates in the preparation of non-sedating antihistamine-type active pharmaceutical ingredients.

Optically active 4-(tert-butoxycarbonyl)piperazine compound, and method for producing the same

There is provided a 4-(tert-butoxycarbonyl)piperazine compound of formula (1) wherein X denotes a chlorine atom, a C1-C3 alkyl group or a C1-C3 alkoxy group, an optical isomer present therein.