1031224-07-3Relevant academic research and scientific papers
NOVEL BENZIMIDAZOLE LINKED PYRROLO[2,1-Q[1,4] BENZODIAZEPINE HYBRIDS AS POTENTIAL ANTITUMOUR AGENTS AND PROCESS FOR THE PREPARATION THEREOF
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Page/Page column 15-16, (2009/10/22)
The present invention provides a compounds of general formula (8), (11) and (14), useful as potential antitumour agents against human cancer cell lines. The present invention further provides a process for the preparation of pyrrolo [2,1-c][1,4]benzodiaze
Synthesis of new benzimidazole linked pyrrolo[2,1-c][1,4]benzodiazepine conjugates with efficient DNA-binding affinity and potent cytotoxicity
Kamal, Ahmed,Praveen Kumar,Sreekanth,Seshadri,Ramulu
, p. 2594 - 2598 (2008/12/21)
The synthesis of new benzimidazole linked pyrrolobenzodiazepine conjugates is described. Some of these conjugates show significant DNA-binding affinity and, a representative compound 4c shows promising in vitro cytotoxicity against a number of human cance
