1031335-08-6Relevant articles and documents
HETEROARYL AMIDES AS TYPE I GLYCINE TRANSPORT INHIBITORS
-
Page/Page column 51; 52, (2008/12/06)
The present invention relates to a series of substituted heteroaryl amides of the Formula I, wherein HET, A, X1 -X4, and R1-R12 groups are defined as in the specification, that exhibit activity as glycine transport inhibitors, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their use for the enhancement of cognition and the treatment of the positive and negative symptoms of schizophrenia and other psychoses in mammals, including humans.