1031367-57-3

Basic information

• Product Name: (6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)(4'-methoxybiphenyl-4-yl)methanone
• CAS NO: 1031367-57-3
• Molecular Weight: 403.478
• Mol File: 1031367-57-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)(4'-methoxybiphenyl-4-yl)methanone(CAS DataBase Reference)
• NIST Chemistry Reference: (6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)(4'-methoxybiphenyl-4-yl)methanone(1031367-57-3)
• EPA Substance Registry System: (6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)(4'-methoxybiphenyl-4-yl)methanone(1031367-57-3)

Safety Data

• Hazardous Substances Data: 1031367-57-3(Hazardous Substances Data)

Upstream product

• 1745-07-9 6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline 
• 67132-14-3 4′-methoxy-[1,1′-biphenyl]-4-carbonyl chloride 

Downstream Products

• 1031367-67-5 6,7-dimethoxy-2-(4'-methoxybiphenyl-4-ylmethyl)-1,2,3,4-tetrahydroisoquinoline 

Relevant articles and documents

4-Biphenyl and 2-naphthyl substituted 6,7-dimethoxytetrahydroisoquinoline derivatives as potent P-gp modulators

Starting from lead compound 1 (EC50 = 1.64 μM), its non-basic nucleus has been conformationally restricted by 4-biphenyl and 2-naphthyl moieties. In each series we investigated if the presence of H-bond donor or acceptor substituents, the basic