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CyclohexylsulfaMoyl Chloride, with the molecular formula C6H11ClO2S, is a chemical compound that exists as a clear, colorless to light yellow liquid with a pungent odor. It is recognized for its role as a sulfonating agent in various organic syntheses, particularly in the production of pharmaceuticals, dyes, and agrochemicals. Its reactivity with amines, alcohols, and phenols to form sulfonamides, sulfonates, and sulfonamides highlights its versatility as an intermediate in manufacturing processes. Moreover, CyclohexylsulfaMoyl Chloride is utilized in the preparation of the Makula reagent for detecting macrocyclic compounds in chemical analysis. Due to its corrosive nature, it requires careful handling to prevent skin and eye irritation.

10314-35-9

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10314-35-9 Usage

Uses

Used in Pharmaceutical Industry:
CyclohexylsulfaMoyl Chloride is used as a sulfonating agent for the synthesis of various pharmaceutical compounds. Its ability to react with different functional groups makes it a valuable intermediate in the development of new drugs.
Used in Dye Industry:
In the dye industry, CyclohexylsulfaMoyl Chloride serves as a sulfonating agent, contributing to the production of a range of dyes with specific properties and applications.
Used in Agrochemical Industry:
CyclohexylsulfaMoyl Chloride is utilized as a key intermediate in the synthesis of agrochemicals, enhancing the development of effective products for agricultural applications.
Used in Chemical Analysis:
CyclohexylsulfaMoyl Chloride is used in the preparation of the Makula reagent, which is essential for the detection of macrocyclic compounds in chemical analysis, aiding in the identification and characterization of these compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 10314-35-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,3,1 and 4 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 10314-35:
(7*1)+(6*0)+(5*3)+(4*1)+(3*4)+(2*3)+(1*5)=49
49 % 10 = 9
So 10314-35-9 is a valid CAS Registry Number.

10314-35-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name N-cyclohexylsulfamoyl chloride

1.2 Other means of identification

Product number -
Other names cyclohexylsulfamyl chloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:10314-35-9 SDS

10314-35-9Relevant academic research and scientific papers

Structure activity studies on sulfamate sweeteners

Benson,Spillane

, p. 869 - 872 (1976)

The structure activity relationships governing sulfamate sweeteners are reviewed under the headings: size of the reduced ring, changes in the sulfamate function, substitution of hydrogen in the ring, and substitution of carbon in the ring and open chain c

Potent and selective, sulfamide-based human β3-adrenergic receptor agonists

Dow, Robert L.,Paight, Ernest S.,Schneider, Steven R.,Hadcock, John R.,Hargrove, Diane M.,Martin, Kelly A.,Maurer, Tristan S.,Nardone, Nancy A.,Tess, David A.,DaSilva-Jardine, Paul

, p. 3235 - 3240 (2007/10/03)

A series of sulfamide-based analogs related to L-796568 were prepared and evaluated for their biological activity at the human β3- adrenergic receptor (AR). This modification allows for a significant reduction in molecular weight, while maintai

THROMBIN INHIBITORS

-

Page 24; 25, (2010/02/07)

The present invention relates to a compound having formula I:and pharmaceutically acceptable salts thereof. The compounds of formula I and pharmaceutical compositions containing them are of the class of thrombin inhibitors which are useful as anticoagulants.

Thrombin inhibitors

-

, (2008/06/13)

The present invention relates to a compound having formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I and pharmaceutical compositions containing them are of the class of thrombin inhibitors which are useful as anticoagula

Chemical and Biological Reactivity of Sulfamidopenicillins

Davern, Peter,Sheehy, James,Smyth, Timothy

, p. 381 - 388 (2007/10/02)

A number of semisynthetic penicillins bearing a sulfamido side chain at the 6-position have been prepared and their chemical and biological reactivity examined.The compounds do not show antibiotic activity against Escherichia coli but do show activity aga

BASICITY OF NITROGEN-SULPHUR(VI) COMPOUNDS. PART 5. IONIZATION OF TRISUBSTITUTED SULPHAMIDES

McDermott, Sean D.,Burke, Padraig O.,Spillane, William J.

, p. 499 - 502 (2007/10/02)

The ionization equilibria in base of 27 trisubstituted sulphamides, mainly represented by the following series: X-C6H4NHSO2NR2R1, where NR2R1=piperidyl, morpholinyl, and NnPr2, and RHNSO2NR2R1/s

Versatile Synthesis of Sulphamate Esters by Phase-transfer Methods

Spillane, William J.,Taheny, Anne P.,Kearns, M. Mary

, p. 677 - 680 (2007/10/02)

The syntheses of sulphamate esters of the general types R1R2NSO3R3, RNHSO3R3, and H2NSO3R3, where R3 may be aliphatic or aromatic, have been achieved in good yield by reaction of the appropriate sulphamoyl chlorides with alcohols and phenols under mild phase-transfer conditions.The present methods have led to generally higher yields, and to shorter reaction times and lower reaction temperatures than were hitherto found necessary.The prior preparation of the alkoxide has also been obviated.Some esters have been rearranged to the isomeric betaines.

Manufacture of sulfamic acid halides

-

, (2008/06/13)

Sulfamic acid halides are produced by reaction of sulfamic acids with phosphorus pentahalide in the presence of phosphorus oxyhalide in specific molar ratios and in the presence of halohydrocarbons. The products, some of which are new compounds, are starting materials for the manufacture of plant protection agents, dyes and pharmaceuticals.

N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same

-

, (2008/06/13)

The case involves novel N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidine and processes for preparing same. The N-pyrazinecarbonyl-N'-substituted-sulfamoylguanidines are excellent eukalemic agents possessing diuretic and natriuretic properties.

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