10314-35-9

Basic information

• Product Name: CyclohexylsulfaMoyl Chloride
• Synonyms: CyclohexylsulfaMoyl Chloride;N-cyclohexylsulfamoyl chloride
• CAS NO: 10314-35-9
• Molecular Formula: C₆H₁₂ClNO₂S
• Molecular Weight: 197.68298
• Mol File: 10314-35-9.mol
• Article Data: 9

Chemical Properties

• Boiling Point: 105 °C(Press: 0.15 Torr)
• Appearance: /
• Density: 1.32±0.1 g/cm3(Predicted)
• PKA: 7.34±0.20(Predicted)
• CAS DataBase Reference: CyclohexylsulfaMoyl Chloride(CAS DataBase Reference)
• NIST Chemistry Reference: CyclohexylsulfaMoyl Chloride(10314-35-9)
• EPA Substance Registry System: CyclohexylsulfaMoyl Chloride(10314-35-9)

Safety Data

• Hazardous Substances Data: 10314-35-9(Hazardous Substances Data)

Usage

General Description

CyclohexylsulfaMoyl Chloride is a chemical compound with the molecular formula C6H11ClO2S. It is a clear, colorless to light yellow liquid with a pungent odor. CyclohexylsulfaMoyl Chloride is commonly used as a sulfonating agent in organic synthesis, particularly in the production of pharmaceuticals, dyes, and agrochemicals. It reacts with amines, alcohols, and phenols to form sulfonamides, sulfonates, and sulfonamides, making it a versatile intermediate in the manufacturing process. Additionally, CyclohexylsulfaMoyl Chloride is also used in the preparation of Makula reagent, a reagent for the detection of macrocyclic compounds in chemical analysis. It is important to handle this compound with proper safety precautions, as it is corrosive and can cause skin and eye irritation upon contact.

Upstream product

• 108-91-8 cyclohexylamine 
• 139-05-9 sodium cyclamate 
• 100-88-9 cyclohexylsulfamic acid 

Downstream Products

• 95881-58-6 C₉H₁₉N₃O₂S₂ 
• 95881-61-1 C₁₀H₂₁N₃O₂S₂ 
• 105556-02-3 C₂₂H₂₈N₄O₄S 
• 154816-73-6 diphenylmethyl 6-cyclohexylsulfamidopenicillanate 
• 1026054-90-9 C₁₈H₂₂N₂O₆S 
• 95308-87-5 C₁₃H₂₀N₂O₂S 
• 95308-90-0 C₁₂H₁₇ClN₂O₂S 
• 81851-28-7 Cyclohexyl-sulfamic acid tert-butyl ester 
• 58044-82-9 N-Cyclohexylphenacylsulfonamid 
• 1417628-92-2 Chas-DPhe(p-NH₂)-Phe(p-NH₂)-OMe 
• 1417628-91-1 Chas-DPhe(p-NO₂)-Phe(p-NO₂)-OMe 

Relevant articles and documents

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Potent and selective, sulfamide-based human β3-adrenergic receptor agonists

A series of sulfamide-based analogs related to L-796568 were prepared and evaluated for their biological activity at the human β3- adrenergic receptor (AR). This modification allows for a significant reduction in molecular weight, while maintai

Thrombin inhibitors

The present invention relates to a compound having formula I: and pharmaceutically acceptable salts thereof. The compounds of formula I and pharmaceutical compositions containing them are of the class of thrombin inhibitors which are useful as anticoagula

BASICITY OF NITROGEN-SULPHUR(VI) COMPOUNDS. PART 5. IONIZATION OF TRISUBSTITUTED SULPHAMIDES

The ionization equilibria in base of 27 trisubstituted sulphamides, mainly represented by the following series: X-C6H4NHSO2NR2R1, where NR2R1=piperidyl, morpholinyl, and NnPr2, and RHNSO2NR2R1/s