1031401-20-3Relevant academic research and scientific papers
Discovery of a 2-hydroxyacetophenone derivative as an outstanding linker to enhance potency and β-selectivity of liver X receptor agonist
Koura, Minoru,Yamaguchi, Yuki,Kurobuchi, Sayaka,Sumida, Hisashi,Watanabe, Yuichiro,Enomoto, Takashi,Matsuda, Takayuki,Okuda, Ayumu,Koshizawa, Tomoaki,Matsumoto, Yuki,Shibuya, Kimiyuki
supporting information, p. 3436 - 3446 (2016/07/21)
Our research found that the 2-hydroxyacetophenone derivative is an outstanding linker between the 1,1-bistrifluoromethylcarbinol moiety and the imidazolidine-2,4-dione moiety to enhance the potency and β-selectivity of liver X receptor (LXR) agonist in ou
SUBSTITUTED CARBINOL COMPOUND
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Page/Page column 25, (2009/09/26)
There is provided a novel LXRβ agonist useful as a preventative and/or therapeutic agent for arteriosclerosis; arteriosclerosis such as those resulting from diabetes; hyperlipidemia; hypercholesterolemia; lipid-related diseases; inflammatory diseases caus
