1031421-19-8Relevant articles and documents
Synthetic studies toward the total synthesis of amphidinolide H1
Deng, Lisheng,Ma, Zhixiong,Zhao, Gang
, p. 728 - 732 (2008)
A convergent synthesis of the macrolide core as the immediate precursor to amphidinolide H1 is described, which features a palladium-catalyzed Stille cross-coupling, a methyl ketone diastereoselective aldol reaction, a Mitsunobu esterification, and an intramolecular ring-closing metathesis (RCM) reaction to construct the 26-membered macrocycle as key steps. Georg Thieme Verlag Stuttgart.