1031438-93-3 Usage
Uses
Used in Organic Synthesis:
BORONIC ACID, B-(2,3-DIMETHOXY-4-PYRIDINYL)is used as a reagent in Suzuki-Miyaura cross-coupling reactions, which are crucial for the formation of carbon-carbon bonds in organic molecules. This application is vital for the development of complex organic structures.
Used in Pharmaceutical Research and Development:
In the pharmaceutical industry, BORONIC ACID, B-(2,3-DIMETHOXY-4-PYRIDINYL)serves as a building block in the synthesis of biologically active compounds, including potential pharmaceuticals. Its unique structure allows for the creation of new drugs with specific therapeutic properties.
Used in Agrochemicals:
This boronic acid derivative is also utilized in the synthesis of agrochemicals, contributing to the development of effective compounds for agricultural applications, such as pesticides and herbicides.
Used as a Fluorescent Probe in Biological Research:
BORONIC ACID, B-(2,3-DIMETHOXY-4-PYRIDINYL)has potential as a fluorescent probe for detecting and quantifying certain biomolecules in biological samples. This use allows for the advancement of research in molecular biology and related fields, facilitating the study of biomolecular interactions and mechanisms.
Check Digit Verification of cas no
The CAS Registry Mumber 1031438-93-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,3,1,4,3 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1031438-93:
(9*1)+(8*0)+(7*3)+(6*1)+(5*4)+(4*3)+(3*8)+(2*9)+(1*3)=113
113 % 10 = 3
So 1031438-93-3 is a valid CAS Registry Number.
1031438-93-3Relevant academic research and scientific papers
(Dimethoxy- and dihalopyridyl)boronic acids and highly functionalized heteroarylpyridines by Suzuki cross-coupling reactions
Smith, Amy E.,Clapham, Kate M.,Batsanov, Andrei S.,Bryce, Martin R.,Tarbit, Brian
experimental part, p. 1458 - 1463 (2009/04/04)
We report the synthesis of (2,6-dimethoxy-3-pyridyl)boronic acid (2), (2,3-dimethoxy-4-pyridyl)boronic acid (4), (2,6-difluoro-3-pyridyl)boronic acid (6), (2,6-dichloro-3-pyridyl)-boronic acid (8) and (2,3-dichloro-4-pyridyl) boronic acid (10) by directed ortho-metalation reactions on the corresponding disubstituted pyridine precursor, followed by the reaction with triisopropyl borate (TPB) or trimethyl borate. The reactivity of the pyridylboronic acids with heteroaryl halides in Suzuki-Miyaura cross-coupling reactions has been evaluated. New highly functionalized heteroarylpyridine derivatives have thereby been obtained in moderate to high yields. The reaction of 8 and 3-amino-2-chloropyridine yielded the rare 5H-pyrrolo[2,3-b:4,5-b′] dipyridine (i.e. 1,5-diazacarbazole) ring system by sequential cross-coupling and intramolecular cyclisation reactions. The X-ray crystal structures are reported for the pyridylboronic acids 2, 4, 8 and 10. Wiley-VCH Verlag GmbH & Co. KGaA, 2008.
