10315-38-5

Usage

Structure

Bicyclic with a diketone functional group

Natural Occurrence

Found in plants such as Securinega suffruticosa

Medicinal Properties

Studied for potential medicinal properties

Biological Activities

Anti-tumor, anti-convulsant, and GABA receptor modulating properties

Potential Treatments

Investigated for neurological disorders such as epilepsy and neurodegenerative diseases

Drug Development

Studied as a lead compound in the development of new drugs

InChI:InChI=1/C10H7NO2/c12-9-5-6-10(13)11-8-4-2-1-3-7(8)9/h1-6H,(H,11,13)

Upstream product

• 125240-97-3 2,3,4,5-tetrahydro-2,5-dioxo-3,4-epoxybenzazepine 
• 130-15-4 [1,4]naphthoquinone 

Downstream Products

• 125241-02-3 1-Amino-4-nitro-2-(2,3-epoxy-4-keto)phenylbutanoic Acid Nitrate 
• 55764-56-2 6-nitro-2-oxo-1,2-dihydroquinoline-4-carboxylic acid 
• 15733-89-8 2-quinolone-4-carboxylic acid 
• 16511-38-9 1H-[1]benzazepin-2,5(3H,4H)-dione 
• 35587-74-7 2,3-Dioxo-2,3-dihydro-1H-1-benzazepin 
• 142273-18-5 paullone 

Relevant academic research and scientific papers

Synthesis of pyrrolo[3,4-c][1]benzazepine-4,10(2H,5H)-dione, a model system useful for the design of 11-oxosibiromycinone analogues

The synthesis of pyrrolo[3,4-c][1]benzazepine-4,10(2H,5H)-dione, a compound related to 11-oxosibiromycinone, is described. 2-Methyl-, 5-methyl- and 2,5-dimethylpyrrolo[3,4-c][1]benzazepine-4,10(2H,5H)-dione have been also prepared. The title compound has been synthesized either by ring enlargement of 2H-benz[f]isoindole-4,9-dione or by TosMIC addition to 1H-1-benzazepin-2,5-dione.

Chemistry, Binding Affinities, and Behavioral Properties of a New Class of "Antineophobic" Mitochondrial DBI Receptor Complex (mDRC) Ligands

The mitochondrial DBI receptor complex (mDRC; previously called the peripheral benzodiazepine receptors) is linked to the production of neurosteroids such as pregnenolone sulfate, dehydroepiandrosterone sulfate, and others.In order to gain further informa

Some Derivatives of Benzazepine. Part III

We report the synthesis by two routes, of hitherto unknown 3,4-epoxy-2,3,4,5-tetrahydrobenzazepine-2,5-dione and hence a new route to 2,3,4,5-tetrahydrobenzazepine-2,4,5-triones which are precursors of 2-quinolonecarboxylic acids.

1-Benzazepines and their pharmaceutical uses

Pharmaceutical compositions comprising 1-benzazepinediones of the formula: STR1 wherein: X and Y are independently O, S, NR or CH-R; A and B are independently H, halo, OH, OR, CF3 or R; and R is H, lower alkyl, aryl, aralkyl or aminoalkyl, are useful as antiallergic agents.