10315-38-5

Basic information

• Product Name: 1H-1-Benzazepine-2,5-dione
• Synonyms: 1H-1-Benzazepine-2,5-dione;(Z)-1H-benzo[b]azepine-2,5-dione
• CAS NO: 10315-38-5
• Molecular Formula: C₁₀H₇NO₂
• Molecular Weight: 173.16808
• Mol File: 10315-38-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 387.2°Cat760mmHg
• Flash Point: 183.9°C
• Appearance: /
• Density: 1.27g/cm³
• Vapor Pressure: 3.36E-06mmHg at 25°C
• Refractive Index: 1.593
• CAS DataBase Reference: 1H-1-Benzazepine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-1-Benzazepine-2,5-dione(10315-38-5)
• EPA Substance Registry System: 1H-1-Benzazepine-2,5-dione(10315-38-5)

Safety Data

• Hazardous Substances Data: 10315-38-5(Hazardous Substances Data)

Usage

Structure

Bicyclic with a diketone functional group

Natural Occurrence

Found in plants such as Securinega suffruticosa

Medicinal Properties

Studied for potential medicinal properties

Biological Activities

Anti-tumor, anti-convulsant, and GABA receptor modulating properties

Potential Treatments

Investigated for neurological disorders such as epilepsy and neurodegenerative diseases

Drug Development

Studied as a lead compound in the development of new drugs

InChI:InChI=1/C10H7NO2/c12-9-5-6-10(13)11-8-4-2-1-3-7(8)9/h1-6H,(H,11,13)

Upstream product

• 130-15-4 [1,4]naphthoquinone 
• 125240-97-3 2,3,4,5-tetrahydro-2,5-dioxo-3,4-epoxybenzazepine 

Downstream Products

• 125241-02-3 1-Amino-4-nitro-2-(2,3-epoxy-4-keto)phenylbutanoic Acid Nitrate 
• 55764-56-2 6-nitro-2-oxo-1,2-dihydroquinoline-4-carboxylic acid 
• 15733-89-8 2-quinolone-4-carboxylic acid 
• 35587-74-7 2,3-Dioxo-2,3-dihydro-1H-1-benzazepin 
• 16511-38-9 1H-[1]benzazepin-2,5(3H,4H)-dione 
• 142273-18-5 paullone 

Relevant articles and documents

Synthesis of pyrrolo[3,4-c][1]benzazepine-4,10(2H,5H)-dione, a model system useful for the design of 11-oxosibiromycinone analogues

The synthesis of pyrrolo[3,4-c][1]benzazepine-4,10(2H,5H)-dione, a compound related to 11-oxosibiromycinone, is described. 2-Methyl-, 5-methyl- and 2,5-dimethylpyrrolo[3,4-c][1]benzazepine-4,10(2H,5H)-dione have been also prepared. The title compound has been synthesized either by ring enlargement of 2H-benz[f]isoindole-4,9-dione or by TosMIC addition to 1H-1-benzazepin-2,5-dione.

Some Derivatives of Benzazepine. Part III

We report the synthesis by two routes, of hitherto unknown 3,4-epoxy-2,3,4,5-tetrahydrobenzazepine-2,5-dione and hence a new route to 2,3,4,5-tetrahydrobenzazepine-2,4,5-triones which are precursors of 2-quinolonecarboxylic acids.